LEGIONELLA MIP PEPTIDE CAN INDUCE HUMORAL IMMUNE RESPONSE IN THE EXPERIMENTAL RABBITS

  • พลากร เค้าแคน
  • สรศักดิ์ อินทรสูต
  • อมรรัตน์ อินทรสูต
Keywords: Legionella pneumophila, Macrophage infectivity potentiator

Abstract

This study in the topic of “Legionella Mip peptide can induce humoral immune response in the experimental rabbits” aim to verify the immunogenic properties of macrophage infectivity potentiator protein in inducing of humoral immune response in experimental rabbits. The synthetic Legionella Mip protein including Mip peptide 1 and Mip peptide 2 were subcutaneous injected into separating rabbit group within 125 days. Different rabbit anti-Mip polyclonal antibody level were determined by indirect enzyme-linked immunosorbent assay (ELISA). Rabbit immunized with Mip peptide 1 produced anti-Mip antibodies higher than the rabbit immunized with Mip peptide 2.

 

Published
2018-09-01